Czterdzieści cztery nie drukowane dokumenty arcybiskupa Jarosława z lat 1343-1372
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Dmd065193 1372..1380
Trimethoprim (TMP) has been widely used since the 1960s, both alone and in combination with sulfamethoxazole. Unfortunately, information regarding the role that cytochrome P450 enzymes (P450s) play in the formation of TMP primary metabolites is scarce. Hence, we undertook in vitro studies to identify and more fully characterize the P450s that catalyze formation of six TMP primary metabolites: T...
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The International Mouse Phenotyping Consortium (IMPC) is a major international effort to explore the effects of knocking out 20,000 genes in the mouse. A new study by White and colleagues, published in the current issue of Disease Models & Mechanisms, demonstrates the usefulness of lacZ in situ reporter expression patterns in extending our understanding of genotype-phenotype relationships as pa...
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EPITHELIUM-FIBRE CELL COUPLING IN THE EYE LENS PRESCOTT, A.R., DAHM. R.. HUTCHESON, A.M., QUIN!-AN. R.A., VANMARLE. J.‘, & VRENSEN. G§. Department of Biochemistry, University of Dundee, Medical Sciences Institute, Dundee, DDl 4HN. Scotland. * Department of Electron Microscopy, Faculty of Medicine, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands. 5 Department of Morp...
متن کاملMolecules 2000, 5, 1372-1378
Synthesis and Photochemical Cyclization of a Novel EnyneCarbodiimide Michael Schmittel,* David Rodríguez 1 and Jens-Peter Steffen FB 8 OC1 (Chemie und Biologie), Universität Siegen, Adolf-Reichwein-Strasse, D-57068 Siegen, Germany. Tel. (+49)-271-4356, Fax (+49) 271-3270. E-mail: [email protected]. 1 Present address: Facultad de Química, Universidad de Santiago de Compostela, Spain...
متن کاملNpgrj_nn_1531 1343..1349
In Alzheimer disease, increased b-secretase (BACE1) activity has been associated with neurodegeneration and accumulation of amyloid precursor protein (APP) products. Thus, inactivation of BACE1 could be important in the treatment of Alzheimer disease. In this study, we found that lowering BACE1 levels using lentiviral vectors expressing siRNAs targeting BACE1 reduced amyloid production and the ...
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ژورنال
عنوان ژورنال: Archiwa, Biblioteki i Muzea Kościelne
سال: 2020
ISSN: 2545-3491,0518-3766
DOI: 10.31743/abmk.7744